Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility.

Henriette H NerildAndreas BrøndenIda M GetherPernille H HellmannMille BaekdalMatthew P GillumJens S SvenningsenBolette HartmannNaveen RathorHanna Angelene Kudiyanur MunirajuJens F RehfeldJens J HolstTina Vilsbøll David Peick Sonne Filip K Krag Knop

Published in: Diabetes, obesity & metabolism (2023)

Compared with placebo, treatment with liraglutide decreased postprandial FGF19 and GLP-2 concentrations and increased postprandial CCK concentrations, which may explain the delayed postprandial gallbladder refilling observed in individuals with obesity treated with liraglutide.

Keyphrases

blood glucose
metabolic syndrome
insulin resistance
type diabetes
weight loss
randomized controlled trial
escherichia coli
blood pressure
biofilm formation
skeletal muscle
body mass index
pseudomonas aeruginosa
replacement therapy
double blind
high fat diet induced
study protocol