Quantitative MR evaluation of the infrapatellar fat pad for knee osteoarthritis: using proton density fat fraction and T2* relaxation based on DIXON.

Yanjun ChenXintao ZhangMianwen LiLijie ZhongYukun DingYaru ZhangXueting DuXianfu MoJialing ChenQianmin ChenWenhua HuangShizhen ZhongXiaodong Zhang

Published in: European radiology (2022)

• Fat fraction (FF) and T2* relaxation based on DIXON imaging are novel methods to quantitatively assess the infrapatellar fat pad for knee osteoarthritis (KOA) progression in older adults. • The alterations of FF and T2* using mDIXON technique in IFP were associated with knee structural abnormalities and clinical symptoms. • FF and T2* alternations in IFP can serve as the new imaging biomarkers for fast, simple, and noninvasive assessment in KOA.

Keyphrases

knee osteoarthritis
adipose tissue
high resolution
fatty acid
physical activity
single molecule
total knee arthroplasty
mass spectrometry
sleep quality
contrast enhanced
fluorescence imaging