Role of Synaptophysin, Chromogranin and CD56 in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation: a retrospective large-scale study on 1170 tissue samples.
Katharina KriegsmannChristiane ZgorzelskiThomas MuleyPetros ChristopoulosMichael ThomasHauke WinterMartin EichhornFlorian EichhornMoritz von WinterfeldEsther HerpelBenjamin GoeppertAlbrecht StenzingerFelix J F HerthArne WarthMark KriegsmannPublished in: BMC cancer (2021)
We report on a cohort of 1170 cases that synaptophysin, chromogranin and CD56 are commonly expressed in ADC and SqCC and that their expression has no impact on survival, supporting the current best practice guidelines.