The nature of human IL-6.

Published in: The Journal of experimental medicine (2019)

Countless functions have been attributed experimentally to IL-6. In this issue of JEM, Spencer et al. (https://doi.org/10.1084/jem.20190344) reveal essential, nonredundant functions of human IL-6. Patients with genetic deficiencies of the IL-6 receptor suffer from "hyper IgE syndrome."

Keyphrases

endothelial cells
genome wide
pluripotent stem cells
dna methylation
case report
binding protein