Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of MAPK, NF-κB and PI3K-Akt signaling networks.
Md Areeful HaqueIbrahim JantanHemavathy HarikrishnanWaqas AhmadPublished in: BMC complementary medicine and therapies (2020)
The results suggested that T. crispa extract stimulated the MyD88-dependent signaling pathways by upregulating the various immune inflammatory related parameters.