Randomized clinical trials comparing antibiotic therapy with appendicectomy for uncomplicated acute appendicitis: meta-analysis.

Philip J J Herrod Alex T Kwok Dileep N Lobo

Published in: BJS open (2022)

Earlier optimism regarding the benefits of antibiotic therapy for uncomplicated acute appendicitis does not persist at the same level now that further, large trials have been included. If antibiotic treatment is to be offered routinely as first-line therapy, patients should be counselled appropriately.

Keyphrases

systematic review
end stage renal disease
newly diagnosed
urinary tract infection
randomized controlled trial
clinical trial
cell therapy