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HLH Syndrome in a Community Hospital: The Challenge of an Early Diagnosis.

Yuval WagnerDganit AdamGalit Pomeranz EngelbergAvishalom PomeranzYoav H Messinger
Published in: Pediatric health, medicine and therapeutics (2024)
Children presenting with prolonged fever and abnormal blood counts should be evaluated with ferritin, triglycerides, and fibrinogen levels which indicate possible HLH. Early intervention with corticosteroids and/or IVIG may prevent deterioration, spare them from chemotherapy and provide time for more elaborate testing to identify true HLH. Unfortunately, mortality remains a significant risk for these children.
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