High Expression of VSTM2L Induced Resistance to Chemoradiotherapy in Rectal Cancer through Downstream IL-4 Signaling.

Hao Liu Zhenzhan Zhang Peilin Zhen Meijuan Zhou

Published in: Journal of immunology research (2021)

The high expression of VSTM2L induced resistance to CRT, and adverse survival outcomes served as a prognostic factor in patients with rectal cancer receiving pCRT, suggesting that VSTM2L high expression may be a potential resistant predictable biomarker for LARC patients receiving pCRT.

Keyphrases

rectal cancer
poor prognosis
locally advanced
prognostic factors
high glucose
diabetic rats
binding protein
squamous cell carcinoma
oxidative stress
heart failure
risk assessment
radiation therapy
human health
left ventricular
stress induced