Maternal Pragmatic Language Difficulties in the FMR1 Premutation and the Broad Autism Phenotype: Associations with Individual and Family Outcomes.
Jessica KlusekAngela John ThurmanLeonard AbbedutoPublished in: Journal of autism and developmental disorders (2021)
Broader phenotypes associated with genetic liability, including mild difficulties with pragmatic language skills, have been documented in mothers of children with autism spectrum disorder (ASD) and mothers of children with fragile X syndrome (FXS). This study investigated the relationship between pragmatic difficulties and indicators of maternal well-being and family functioning. Pragmatic difficulty was associated with loneliness in mothers of children with ASD or FXS, and with depression, decreased life satisfaction, and poorer family relationship quality in mothers of children with FXS only. Results inform subtle maternal pragmatic language difficulties as a risk factor that that may contribute to reduced health and well-being, informing tailored support services to better meet the unique needs of families of children with ASD or FXS.
Keyphrases
- autism spectrum disorder
- young adults
- study protocol
- intellectual disability
- healthcare
- attention deficit hyperactivity disorder
- mental health
- public health
- risk factors
- primary care
- birth weight
- type diabetes
- adipose tissue
- clinical trial
- pregnant women
- social support
- smoking cessation
- high resolution
- risk assessment
- health promotion
- high speed