Sinonasal chondrosarcoma in a llama.
Arthur ChengKatharine HorzmannJi-Hang YinPatricia TitosJenna E BayneRachel L A L T NetoPublished in: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc (2024)
A 14-y-old intact female llama ( Lama glama ) was presented for evaluation of a right maxillary swelling of 3-mo duration. Clinically, the animal had mild nasal discharge, abnormal retropulsion of the right eye, and moderate gingival disease. An incisional biopsy of the maxillary mass revealed pleomorphic and mitotically active neoplastic spindle-to-stellate cells organized in haphazard lacunae embedded in abundant chondroid matrix. Given the poor prognosis, euthanasia was elected. Postmortem examination and sectioning of the head exposed a large solid, white, firm mass that vastly expanded the right infraorbital region, extending to the maxilla, effacing the right nasal conchae and ipsilateral zygomatic bone. Collectively, postmortem dissection, cytology, and histopathology of the primary mass supported a diagnosis of sinonasal chondrosarcoma. To our knowledge, this entity had not been reported previously in this species and should be considered a differential for facial deformities in New World camelids.
Keyphrases
- poor prognosis
- chronic rhinosinusitis
- long non coding rna
- fine needle aspiration
- induced apoptosis
- healthcare
- soft tissue
- cell cycle arrest
- cone beam computed tomography
- bone mineral density
- high intensity
- high grade
- single cell
- postmenopausal women
- optic nerve
- endoplasmic reticulum stress
- cell death
- body composition
- duchenne muscular dystrophy