Effect of intensive lifestyle intervention on the association between weight variability and major adverse cardiovascular events in overweight or obese adults with type 2 diabetes mellitus.
Xiangbin ZhongXingfeng XuMenghui LiuPeng WangLixiang HeOdong ChristopherShaozhao ZhangYifen LinYiquan HuangZhenyu XiongXiaodong ZhuangXin-Xue LiaoPublished in: Journal of diabetes investigation (2023)
Among the overweight or obese individuals with type 2 diabetes mellitus, rising weight variability was independently associated with increased MACE risks in the DSE arm. Therefore, a guideline-recommended ILI strategy for weight loss should be adopted to improve cardiovascular outcomes without worrying about the effect of weight fluctuations.
Keyphrases
- weight loss
- cardiovascular events
- bariatric surgery
- roux en y gastric bypass
- gastric bypass
- coronary artery disease
- weight gain
- cardiovascular disease
- randomized controlled trial
- glycemic control
- obese patients
- physical activity
- type diabetes
- body mass index
- emergency department
- metabolic syndrome
- adipose tissue
- insulin resistance
- electronic health record