Translational Modeling of Chloroquine and Hydroxychloroquine Dosimetry in Human Airways for Treating Viral Respiratory Infections.

Aditya Reddy KolliFlorian Calvino-MartinJulia Hoeng

Published in: Pharmaceutical research (2022)

Our analysis provides a framework for extrapolating in vitro effective concentrations of chloroquine and hydroxychloroquine to in vivo dosing regimens for treating viral respiratory infections.

Keyphrases

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endothelial cells
respiratory tract
induced pluripotent stem cells
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