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Association of C-reactive Protein and Partial Mayo Score With Response to Tofacitinib Induction Therapy: Results From the Ulcerative Colitis Clinical Program.

Marla C DubinskyFernando MagroFlavio SteinwurzDavid P HudesmanJami A KinnucanRyan C UngaroMarkus F NeurathNicole KulisekJerome PaulissenChinyu SuDario Ponce de LeonMiguel Regueiro
Published in: Inflammatory bowel diseases (2022)
Patients who achieved clinical response at week 8 had larger decreases in CRP and PMS at week 4 than patients who did not. IndNR who achieved clinical response at week 16 with extended tofacitinib induction had a larger decrease in PMS at week 8 vs those who did not. ClinicalTrials.gov:NCT00787202;NCT01465763;NCT01458951;NCT01470612.
Keyphrases
  • ulcerative colitis
  • randomized controlled trial
  • clinical trial
  • stem cells
  • bone marrow
  • quality improvement
  • study protocol