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Umbilical cord blood DNA methylation in children who later develop type 1 diabetes.

Essi LaajalaUbaid Ullah KalimToni GrönroosOmid RasoolViivi Halla-AhoMikko KonkiRoosa KattelusJuha MykkänenMirja NurmioMari Vähä-MäkiläHenna KallionpääNiina LietzénBishwa R GhimireAsta LaihoHeikki HyötyLaura L EloJorma IlonenOlli H LaitinenRiikka J LundMatej OresicRiitta VeijolaHarri LähdesmäkiJorma ToppariRiitta Lahesmaa
Published in: Diabetologia (2022)
Based on our results, differences between children who progress to type 1 diabetes and those who remain healthy throughout childhood are not yet present in the perinatal DNA methylome. However, we cannot exclude the possibility that such differences would be found in a larger dataset.
Keyphrases
  • type diabetes
  • umbilical cord
  • mesenchymal stem cells
  • dna methylation
  • young adults
  • glycemic control
  • gene expression
  • pregnant women
  • insulin resistance
  • genome wide
  • skeletal muscle
  • childhood cancer