Heikki Hyöty (H Hyöty, Heikki Hyoty)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 21

Top Topics

Dna Methylation

Top Venues

Science advances

Diabetic medicine : a journal of the British Diabetic Association

This page only lists publications with an associated author ORCID identifier.

Publications

Heikki Hyöty, Susanna Kääriäinen, Jutta E Laiho, Gail M Comer, Wei Tian, Taina Härkönen, Jussi P Lehtonen, Sami Oikarinen, Leena Puustinen, Michele Snyder, Francisco León, Mika Scheinin, Olli H Laitinen, Miguel Sanjuan
Safety, tolerability and immunogenicity of PRV-101, a multivalent vaccine targeting coxsackie B viruses (CVBs) associated with type 1 diabetes: a double-blind randomised placebo-controlled Phase I trial. Diabetologia 67 (5) (2024)
Heikki Hyöty, Susanna Kääriäinen, Jutta E Laiho, Gail M Comer, Wei Tian, Taina Härkönen, Jussi P Lehtonen, Sami Oikarinen, Leena Puustinen, Michele Snyder, Francisco León, Mika Scheinin, Olli H Laitinen, Miguel Sanjuan
Safety, tolerability and immunogenicity of PRV-101, a multivalent vaccine targeting coxsackie B viruses (CVBs) associated with type 1 diabetes: a double-blind randomised placebo-controlled Phase I trial. Diabetologia 67 (5) (2024)
Federica Vecchio, Alexia Carré, Daniil Korenkov, Zhicheng Zhou, Paola S Apaolaza, Soile Tuomela, Orlando Burgos-Morales, Isaac Snowhite, Javier Perez-Hernandez, Barbara Brandao, Georgia Afonso, Clémentine Halliez, Alberto Pugliese, Sally C Kent, Maki Nakayama, Sarah J Richardson, Joelle Vinh, Yann Verdier, Jutta E Laiho, Raphael Scharfmann, Michele Solimena, Zuzana Marinicova, Elise Bismuth, Nadine Lucidarme, Janine Sanchez, Carmen Bustamante, Patricia Gomez, Soren Buus, null null, Sylvaine You, Alberto Pugliese, Heikki Hyöty, Teresa Rodriguez-Calvo, Malin Flodström Tullberg, Roberto Mallone
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses. Science advances 10 (10) (2024)
Federica Vecchio, Alexia Carré, Daniil Korenkov, Zhicheng Zhou, Paola S Apaolaza, Soile Tuomela, Orlando Burgos-Morales, Isaac Snowhite, Javier Perez-Hernandez, Barbara Brandao, Georgia Afonso, Clémentine Halliez, Alberto Pugliese, Sally C Kent, Maki Nakayama, Sarah J Richardson, Joelle Vinh, Yann Verdier, Jutta E Laiho, Raphael Scharfmann, Michele Solimena, Zuzana Marinicova, Elise Bismuth, Nadine Lucidarme, Janine Sanchez, Carmen Bustamante, Patricia Gomez, Soren Buus, null null, Sylvaine You, Alberto Pugliese, Heikki Hyöty, Teresa Rodriguez-Calvo, Malin Flodström Tullberg, Roberto Mallone
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses. Science advances 10 (10) (2024)
Heikki Hyöty, Susanna Kääriäinen, Jutta E Laiho, Gail M Comer, Wei Tian, Taina Härkönen, Jussi P Lehtonen, Sami Oikarinen, Leena Puustinen, Michele Snyder, Francisco León, Mika Scheinin, Olli H Laitinen, Miguel Sanjuan
Safety, tolerability and immunogenicity of PRV-101, a multivalent vaccine targeting coxsackie B viruses (CVBs) associated with type 1 diabetes: a double-blind randomised placebo-controlled Phase I trial. Diabetologia 67 (5) (2024)
Federica Vecchio, Alexia Carré, Daniil Korenkov, Zhicheng Zhou, Paola S Apaolaza, Soile Tuomela, Orlando Burgos-Morales, Isaac Snowhite, Javier Perez-Hernandez, Barbara Brandao, Georgia Afonso, Clémentine Halliez, Alberto Pugliese, Sally C Kent, Maki Nakayama, Sarah J Richardson, Joelle Vinh, Yann Verdier, Jutta E Laiho, Raphael Scharfmann, Michele Solimena, Zuzana Marinicova, Elise Bismuth, Nadine Lucidarme, Janine Sanchez, Carmen Bustamante, Patricia Gomez, Soren Buus, null null, Sylvaine You, Alberto Pugliese, Heikki Hyöty, Teresa Rodriguez-Calvo, Malin Flodström Tullberg, Roberto Mallone
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses. Science advances 10 (10) (2024)
Federica Vecchio, Alexia Carré, Daniil Korenkov, Zhicheng Zhou, Paola S Apaolaza, Soile Tuomela, Orlando Burgos-Morales, Isaac Snowhite, Javier Perez-Hernandez, Barbara Brandao, Georgia Afonso, Clémentine Halliez, Alberto Pugliese, Sally C Kent, Maki Nakayama, Sarah J Richardson, Joelle Vinh, Yann Verdier, Jutta E Laiho, Raphael Scharfmann, Michele Solimena, Zuzana Marinicova, Elise Bismuth, Nadine Lucidarme, Janine Sanchez, Carmen Bustamante, Patricia Gomez, Soren Buus, null null, Sylvaine You, Alberto Pugliese, Heikki Hyöty, Teresa Rodriguez-Calvo, Malin Flodström Tullberg, Roberto Mallone
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses. Science advances 10 (10) (2024)
Heikki Hyöty, Susanna Kääriäinen, Jutta E Laiho, Gail M Comer, Wei Tian, Taina Härkönen, Jussi P Lehtonen, Sami Oikarinen, Leena Puustinen, Michele Snyder, Francisco León, Mika Scheinin, Olli H Laitinen, Miguel Sanjuan
Safety, tolerability and immunogenicity of PRV-101, a multivalent vaccine targeting coxsackie B viruses (CVBs) associated with type 1 diabetes: a double-blind randomised placebo-controlled Phase I trial. Diabetologia 67 (5) (2024)
Heikki Hyöty, Susanna Kääriäinen, Jutta E Laiho, Gail M Comer, Wei Tian, Taina Härkönen, Jussi P Lehtonen, Sami Oikarinen, Leena Puustinen, Michele Snyder, Francisco León, Mika Scheinin, Olli H Laitinen, Miguel Sanjuan
Safety, tolerability and immunogenicity of PRV-101, a multivalent vaccine targeting coxsackie B viruses (CVBs) associated with type 1 diabetes: a double-blind randomised placebo-controlled Phase I trial. Diabetologia 67 (5) (2024)
Heikki Hyöty, Susanna Kääriäinen, Jutta E Laiho, Gail M Comer, Wei Tian, Taina Härkönen, Jussi P Lehtonen, Sami Oikarinen, Leena Puustinen, Michele Snyder, Francisco León, Mika Scheinin, Olli H Laitinen, Miguel Sanjuan
Safety, tolerability and immunogenicity of PRV-101, a multivalent vaccine targeting coxsackie B viruses (CVBs) associated with type 1 diabetes: a double-blind randomised placebo-controlled Phase I trial. Diabetologia (2024)
Maria Lönnrot, Kristian F Lynch, Marian Rewers, Lernmark Åke, Kendra Vehik, Beena Akolkar, William Hagopian, Jeffrey Krischer, Rickhard A McIndoe, Jorma Toppari, Anette-Gabriele Ziegler, Joseph F Petrosino, Richard Lloyd, Heikki Hyöty, null null
Gastrointestinal Infections Modulate the Risk for Insulin Autoantibodies as the First-Appearing Autoantibody in the TEDDY Study. Diabetes care (2023)
Jake Lin, Elaheh Moradi, Karoliina Salenius, Suvi Lehtipuro, Tomi Häkkinen, Jutta E Laiho, Sami Oikarinen, Sofia Randelin, Hemang M Parikh, Jeffrey P Krischer, Jorma Toppari, Lernmark Åke, Joseph F Petrosino, Nadim J Ajami, Jin-Xiong She, William A Hagopian, Marian J Rewers, Richard E Lloyd, Kirsi J Granberg, Heikki Hyöty, Matti Nykter, null null
Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection. Nature communications 14 (1) (2023)
Federica Vecchio, Alexia Carré, Daniil Korenkov, Zhicheng Zhou, Paola Apaolaza, Soile Tuomela, Orlando Burgos-Morales, Isaac Snowhite, Javier Perez-Hernandez, Barbara Brandao, Georgia Afonso, Clémentine Halliez, John Kaddis, Sally C Kent, Maki Nakayama, Sarah J Richardson, Joelle Vinh, Yann Verdier, Jutta Laiho, Raphael Scharfmann, Michele Solimena, Zuzana Marinicova, Elise Bismuth, Nadine Lucidarme, Janine Sanchez, Carmen Bustamante, Patricia Gomez, Soren Buus, null null, Sylvaine You, Alberto Pugliese, Heikki Hyöty, Teresa Rodriguez-Calvo, Malin Flodström Tullberg, Roberto Mallone
Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses. bioRxiv : the preprint server for biology (2023)
Amir-Babak Sioofy-Khojine, Sarah J Richardson, Jonathan M Locke, Sami Oikarinen, Noora Nurminen, Antti-Pekka Laine, Kate Downes, Johanna Lempainen, John A Todd, Riitta Veijola, Jorma Ilonen, Olli H Laitinen, Noel G Morgan, Heikki Hyöty, Mark Peakman, Martin Eichmann
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage. Diabetologia 65 (10) (2022)
Essi Laajala, Ubaid Ullah Kalim, Toni Grönroos, Omid Rasool, Viivi Halla-Aho, Mikko Konki, Roosa Kattelus, Juha Mykkänen, Mirja Nurmio, Mari Vähä-Mäkilä, Henna Kallionpää, Niina Lietzén, Bishwa R Ghimire, Asta Laiho, Heikki Hyöty, Laura L Elo, Jorma Ilonen, Olli H Laitinen, Riikka J Lund, Matej Oresic, Riitta Veijola, Harri Lähdesmäki, Jorma Toppari, Riitta Lahesmaa
Umbilical cord blood DNA methylation in children who later develop type 1 diabetes. Diabetologia 65 (9) (2022)
Sami Oikarinen, Lars Krogvold, Bjørn Edwin, Trond Buanes, Olle Korsgren, Jutta E Laiho, Maarit Oikarinen, Johnny Ludvigsson, Oskar Skog, Mahesh Anagandula, Gun Frisk, Heikki Hyöty, Knut Dahl-Jørgensen
Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study. Diabetologia 64 (11) (2021)
Virginia M Stone, Marta Butrym, Minna M Hankaniemi, Amir-Babak Sioofy-Khojine, Vesa P Hytönen, Heikki Hyöty, Malin Flodström Tullberg
Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect. Diabetes 70 (12) (2021)
Leena Hakola, Iris Erlund, David Cuthbertson, Maija E Miettinen, Reija Autio, Anita M Nucci, Taina Härkönen, Jarno Honkanen, Outi Vaarala, Heikki Hyöty, Olli H Laitinen, Jeffrey P Krischer, Sari Niinistö, Suvi M Virtanen, null null
Serum fatty acids and risk of developing islet autoimmunity: A nested case-control study within the TRIGR birth cohort. Pediatric diabetes 22 (4) (2021)
Virginia M Stone, Minna M Hankaniemi, Johanna Lempainen, Amir-Babak Sioofy-Khojine, Ang Lin, I M Diaz Lozano, M A Mazur, V Marjomäki, Karin Loré, Heikki Hyöty, Vesa Pekka Hytönen, Malin Flodström Tullberg
A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates. Science advances 6 (19) (2020)
Marja I Roslund, Riikka Puhakka, Mira Grönroos, Noora Nurminen, Sami Oikarinen, Ahmad M Gazali, Ondrej Cinek, Lenka Kramná, Nathan Siter, Heli K Vari, Laura Soininen, Anirudra Parajuli, Juho Rajaniemi, Tuure Kinnunen, Johanna Lempainen, Heikki Hyöty, Aki Sinkkonen, null null
Biodiversity intervention enhances immune regulation and health-associated commensal microbiota among daycare children. Science advances 6 (42) (2020)
Amir-Babak Sioofy-Khojine, Anni Honkimaa, Heikki Hyöty
A preclinical assessment to repurpose drugs to target type 1 diabetes-associated type B coxsackieviruses. Diabetic medicine : a journal of the British Diabetic Association 37 (11) (2019)