The Clinical Characteristics of Pediatric Non-Infectious Uveitis in Two Tertiary Referral Centers in Turkey.
Fatime Nilüfer YalçındağSirel Gür GüngörMehmet Fatih Kağan DeğirmenciAlmila Sarıgül SezenözZeynep Birsin ÖzçakarEsra BaskınFatma Fatoş YalçınkayaHuban AtillaPublished in: Ocular immunology and inflammation (2019)
Purpose: To report the manifestations, patterns of disease, treatment strategies and outcomes in pediatric patients with noninfectious uveitis.Methods: Demographic information of 76 cases was recorded. Symptoms, anatomic location, laterality, visual acuity (VA), intraocular pressure, associated systemic diseases, therapeutic strategies, side effects, complications were reviewed.Results: Thirty-one patients were diagnosed as uveitis on routine surveillance because of underlying systemic disease. The most common anatomic location was intermediate uveitis (34.2%). Juvenile idiopathic arthritis (JIA) was the most common underlying systemic disease (25%). Glaucoma was the most common complication (7.7%). The patients with refractory uveitis received adalimumab (26.5%), infliximab (4.6%) and tocilizumab (3.1%). The mean first-year VA was between 20/32 and 20/20 in 116/140 eyes.Conclusion: Most pediatric noninfectious uveitis cases have bilateral intermediate uveitis. JIA was the most common systemic association. The first-year VA was good in most eyes which may be due to early use of corticosteroid-sparing agents.
Keyphrases
- juvenile idiopathic arthritis
- disease activity
- end stage renal disease
- public health
- chronic kidney disease
- primary care
- newly diagnosed
- systemic lupus erythematosus
- rheumatoid arthritis
- healthcare
- young adults
- metabolic syndrome
- risk factors
- rheumatoid arthritis patients
- prognostic factors
- physical activity
- social media
- insulin resistance
- skeletal muscle
- patient reported outcomes
- drug induced
- peritoneal dialysis
- patient reported