CHG and PI are effective at lower concentrations than typically used, establishing baselines to support further clinical trials aimed at optimizing wound disinfection. There is no synergistic advantage to using both in combination. Vancomycin is effective at inhibiting the growth of S. epidermidis and S. aureus; however, it stimulates P. aeruginosa biofilm production, suggesting in the rare case of P. aeruginosa PJI, it could exacerbate infection.
Keyphrases
- rare case
- clinical trial
- methicillin resistant staphylococcus aureus
- candida albicans
- biofilm formation
- staphylococcus aureus
- pseudomonas aeruginosa
- drinking water
- signaling pathway
- randomized controlled trial
- cancer therapy
- gram negative
- magnetic resonance imaging
- drug delivery
- cystic fibrosis
- wound healing
- phase iii
- placebo controlled