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Prediction of Cognitive Heterogeneity in Parkinson's Disease: A 4-Year Longitudinal Study Using Clinical, Neuroimaging, Biological and Electrophysiological Biomarkers.

Arnau Puig-DaviSaul-Indra Martinez-HortaLaura Pérez-CarasolAndrea Horta-BarbaIñigo Ruiz-BarrioIgnacio Aracil-BolañosRocío Pérez-GonzálezElisa Rivas-AsensioFrederic SampedroAntonia CampolongoJavier PagonabarragaJaime Kulisevsky
Published in: Annals of neurology (2024)
In the absence of differences in baseline cognitive function and typical markers of neurodegeneration, the further development of an aggressive cognitive decline in PD is associated with increased slow-wave power density and with a different profile of worsening in several posterior-cortical-dependent tasks. ANN NEUROL 2024.
Keyphrases
  • cognitive decline
  • mild cognitive impairment
  • working memory
  • single cell
  • cross sectional
  • neural network