NKG2D (Natural Killer Group 2, Member D) ligand expression and ameloblastoma recurrence: a retrospective immunohistological pilot study.
Mee-Seon KimSoeun JeonHyeon Jeong LeeHyun-Su RiAh-Reum ChoEun Ji ParkJin Song YeoJae-Han KimJiyoun LeePublished in: BMC oral health (2024)
This study identified recurrent cases and loss of MICA/B expression as independent predictors of early ameloblastoma recurrence following surgical resection. The findings suggest that decreased MICA/B expression might undermine NKG2D-mediated tumor immunosurveillance, thereby influencing early recurrence.