CYP19A1 gene expression in the peripheral blood of Brazilian women with breast cancer relapse.

Maria da Conceição Barros-OliveiraDanylo Rafhael Costa-SilvaLarysse Cardoso Campos-VerdesRenato de Oliveira PereiraRozirene Araújo SilvaPaulo de Tarso Moura-BorgesEmerson Brandão SousaAndré Luiz Pinho-SobralPedro Vitor Lopes-CostaAlesse Ribeiro Dos SantosIone Maria Ribeiro Soares-LopesJackeline Lopes VianaMariella de Almeida MeloFidelis Manes NetoEid Gonçalves CoelhoMaria do Socorro Pires E CruzVladimir Costa-SilvaLuiz Henrique GebrimBenedito Borges da Silva

Published in: BMC cancer (2020)

The present study found no significant differences between women with high and low expression of the CYP19A1 gene mRNA or between those in the study group and the control group. However, in women with recurrence, there was increased expression of CYP19A1 mRNA in those who had the luminal hybrid subtype and locoregional relapse and decreased expression in those negative for HER2.

Keyphrases

poor prognosis
gene expression
binding protein
peripheral blood
long non coding rna
copy number