The Regulation of ManLAM-Related Gene Expression in Mycobacterium tuberculosis with Different Drug Resistance Profiles Following Isoniazid Treatment.

Manita YimcharoenSukanya SaikaewUsanee AnukoolPonrut PhunpaeSorasak IntorasootWatchara KasinrerkChatchai TayapiwatanaBordin Butr-Indr

Published in: Infection and drug resistance (2022)

This study establishes a relationship between the antibiotic stress response mechanism and the expression of ManLAM-related genes in MTB samples with diverse drug resistance profiles. The novel gene expression pattern in this work is valuable knowledge that can be applied for TB monitoring and treatment in the future.

Keyphrases

mycobacterium tuberculosis
gene expression
dna methylation
pulmonary tuberculosis
healthcare
poor prognosis
combination therapy
current status