Phase II/III placebo-controlled randomized trial of safety and efficacy of growth hormone treatment in incomplete chronic traumatic spinal cord injury.
Ana Esclarin-RuzInmaculada Rodríguez-CarriónSilvia Ceruelo-AbajoRamiro Palazón-GarciaFernando Ayuga-LoroCarmen Carrasco-LopezMonica Alcobendas-MaestroRosa M Casado-LopezFrancisco Talavera-DiazVanesa Soto-LeónMichela CampoloFrancisco J Romero-GanuzaJose Florensa-VilaDavid Garcia-MarcoMario RotondiAntonio OlivieroPublished in: Spinal cord (2021)
It is important to highlight that our aim was to propose GH as a possible treatment to improve motor functions in incomplete SCI individuals. At least with the doses we used, we think that the therapeutic effects of this approach are not clinically relevant in most subjects with SCI.