Investigation of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions and performance of a rapid diagnostic test for identifying asymptomatic malaria infection in northern Ethiopia, 2015.
Colleen M LeonardAshenafi AssefaJessica N McCafferyCamelia HermanMateusz PlucinskiHeven SimeHussein MohammedAmha KebedeHiwot SolomonMebrahtom HaileMatt MurphyJimee HwangEric RogierPublished in: Malaria journal (2022)
There is evidence of dual pfhrp2/3 gene deletions in the Tigray and Amhara regions of Ethiopia in 2015. As the prevalence of malaria was very low (<ā2%), it is difficult to make strong conclusions on RDT performance, but these results challenge the utility of biomarkers in household surveys in very low transmission settings.