The transcriptomic responses of Atlantic salmon (Salmo salar) to high temperature stress alone, and in combination with moderate hypoxia.
Anne BeemelmannsFábio S ZanuzzoXi XueRebeccah M SandrelliMatthew L RiseA Kurt GamperlPublished in: BMC genomics (2021)
Increasing temperature to 20 °C alone, and in combination with hypoxia, resulted in the differential expression of genes involved in similar pathways in Atlantic salmon. However, the expression responses of heat shock and immune-relevant genes in fish exposed to 20 °C and hypoxia were more affected, and strongly related to phenotypic characteristics (e.g., growth). This study provides valuable information on how these two environmental challenges affect the expression of stress-, metabolic- and immune-related genes and pathways, and identifies potential biomarker genes for improving our understanding of fish health and welfare.
Keyphrases
- heat shock
- genome wide
- poor prognosis
- high temperature
- endothelial cells
- heat stress
- healthcare
- public health
- health information
- binding protein
- mental health
- genome wide identification
- single cell
- long non coding rna
- dna methylation
- bioinformatics analysis
- human health
- heat shock protein
- stress induced
- high intensity
- rna seq
- gene expression
- oxidative stress
- climate change
- transcription factor
- genome wide analysis