Multicentric retrospective analysis of platinum-pemetrexed regimens as first-line therapy in non-squamous non-small cell lung cancer patients: A "snapshot" from clinical practice.
Alessio CortelliniElisabetta GambaleKatia CannitaDavide BroccoAlessandro ParisiLuca NapoleoniFrancesco MaseduLuciana IrtelliMichele De TursiClara NatoliCorrado FicorellaPublished in: Thoracic cancer (2017)
Accurate management allowed us to treat the majority of advanced non-Sq NSCLC patients with PP combination therapy without significant differences in ORR, median PFS, and median OS. Even considering the selection bias, our data seems to confirm the greater effectiveness of cisplatin-based over carboplatin-based regimens.
Keyphrases
- combination therapy
- small cell lung cancer
- clinical practice
- advanced non small cell lung cancer
- randomized controlled trial
- cell therapy
- single cell
- systematic review
- high grade
- electronic health record
- low grade
- high resolution
- phase ii study
- brain metastases
- epidermal growth factor receptor
- data analysis
- machine learning
- phase iii
- mass spectrometry
- artificial intelligence
- study protocol
- smoking cessation