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FLI1 Regulates Histamine Decarboxylase Expression to Control Inflammation Signaling and Leukemia Progression.

Jifen HuJian GaoChunlin WangWuling LiuAnling HuXiao XiaoYi KuangKunlin YuBabu GajendranEldad ZacksenhausWeidong PanYaacov Ben-David
Published in: Journal of inflammation research (2023)
These results suggest a role for the transcription factor FLI1 in inflammation signaling and leukemia progression through HDC and point to the HDC pathway as potential therapeutics for FLI1-driven leukemia.
Keyphrases
  • acute myeloid leukemia
  • bone marrow
  • oxidative stress
  • transcription factor
  • poor prognosis
  • climate change