Cognitive Function Trajectories in Association With the Depressive Symptoms Trajectories in Systemic Lupus Erythematosus Over Time.
Zahi ToumaBahar MoghaddamJiandong SuPatricia P KatzPublished in: Arthritis care & research (2021)
In all, 4 distinct classes of dual cognitive function and depressive symptoms were identified. Persistently low cognitive performance in 28% of patients (classes 1 and 3) did not significantly improve over 7 years. Cognitive impairment was associated with depression status in 9% of patients (class 3). Other factors also predicted latent class membership: ethnicity, education, disease activity, physical functioning, and bodily pain. These results highlight the importance of periodic assessment of cognitive function and of different aspects relevant for assessing and managing cognitive function over time in SLE.
Keyphrases
- depressive symptoms
- disease activity
- end stage renal disease
- systemic lupus erythematosus
- chronic kidney disease
- ejection fraction
- rheumatoid arthritis
- cognitive impairment
- newly diagnosed
- social support
- healthcare
- prognostic factors
- physical activity
- patient reported outcomes
- pain management
- spinal cord
- juvenile idiopathic arthritis
- patient reported
- neuropathic pain