Signalling of multiple interleukin (IL)-17 family cytokines via IL-17 receptor A drives psoriasis-related inflammatory pathways.

Maxim A X Tollenaere J Hebsgaard David Adrian Ewald Paola Lovato Sandra Garcet Xuan Li S D Pilger M L Tiirikainen M Bertelsen James G Krueger Hanne Norsgaard

Published in: The British journal of dermatology (2021)

Several IL-17 ligands signalling through IL-17RA are overexpressed in psoriasis skin and induce similar psoriasis-related inflammatory pathways demonstrating their relevance in relation to therapeutic intervention in psoriasis.

Keyphrases

systemic sclerosis
oxidative stress
randomized controlled trial
atopic dermatitis
rheumatoid arthritis
systemic lupus erythematosus
soft tissue
drug induced