The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers.
Jingwen LiuWei ZhaoLeyu ZhangXi WangPublished in: Cell death discovery (2022)
N 6 -methyladenosine (m 6 A) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a large number of vital biological progressions. With the great improvement of molecular biology, m 6 A and lncRNAs are attracting more attention from researchers and scholars. In this review, we overview the current status of m 6 A and lncRNAs based on the latest research, and propose some viewpoints for future research perspectives.