Sex-specific analysis of the rapid up-titration of guideline-directed medical therapies after a hospitalisation for acute heart failure: insights from the STRONG-HF trial.
Kamilė Čerlinskaitė-BajorėCarolyn S P LamKaren SliwaMarianna AdamoJozine M Ter MaatenValentine LéopoldAlexandre MebazaaBeth DavisonChristopher EdwardsMattia ArrigoMarianela BarrosJan BiegusOvidiu ChioncelAlain Cohen-SolalAlbertino DamascenoRafael DiazGerasimos FilippatosEtienne GayatAntoine KimmounMarco MetraMaria NovosadovaMatteo PagnesiPeter S PangPiotr PonikowskiHadiza SaiduKoji TakagiDaniela TomasoniAdriaan A VoorsGad CotterJelena ČelutkienėPublished in: European journal of heart failure (2023)
The results of the current analyses suggest that a rapid up-titration of GDMT immediately after an AHF hospitalisation can and should be implemented similarly in men and women, as it results in reduction of 180-day all-cause death or HF readmission, quality-of-life improvement in both men and women with a similar safety profile.