Chemical composition and biological evaluation of the essential oil of the flowering aerial parts of Aegopodium alpestre Ledeb.

Aegopodium alpestre Ledeb ( A. alpestre ) is a plant known for its fragrant smell and has been traditionally used to treat influenza. However, despite its widespread use, there is no research on its flowering aerial parts. This study aims to contribute to the understanding the flowering aerial parts by investigating its volatile oil. The essential oil was extracted through hydrodistillation and analysed using GC-MS. The analysis identified 54 compounds, which accounted for 95.16% of the oil composition. The major components are germacrene D (31.68%), β -caryophyllene (16.07%), and ( E )- β -farnesene (7.99%). To evaluate the antioxidant activity of volatile oil, six antioxidant experiments were conducted. The results indicated that volatile oil exhibited significant 2,2'-azino- bis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt and hydroxyl radical scavenging abilities. Furthermore, the antibacterial activity of volatile oil was assessed against four common pathogenic bacteria. The findings demonstrated that volatile oil displayed potent antibacterial activity against Escherichia coli and Aerogenic bacterium .