Platelet mitochondrial respiration and coenzyme Q10 could be used as new diagnostic strategy for mitochondrial dysfunction in rheumatoid diseases.

Anna GvozdjakovaZuzana SumbalováJarmila KucharskáMonika SzamosováLubica ČápováZuzana RausováOľga VančováViliam MojtoPeter LangsjoenPatrik Palacka

Published in: PloS one (2021)

The observed decrease in platelet CoQ10 levels may lead to platelet mitochondrial dysfunction in RA diseases. Determination of platelet mitochondrial function and platelet CoQ10 levels could be used as new diagnostic strategies for mitochondrial bioenergetics in rheumatoid diseases.

Keyphrases

oxidative stress
rheumatoid arthritis
rheumatoid arthritis patients
systemic lupus erythematosus
mass spectrometry
systemic sclerosis
molecularly imprinted
interstitial lung disease
solid phase extraction