Acute severe paediatric asthma: study protocol for the development of a core outcome set, a Pediatric Emergency Reserarch Networks (PERN) study.
Simon S CraigFranz E BablStuart R DalzielCharmaine GrayColin PowellKhalid Al AnsariMark D LyttleDamian RolandJavier BenitoRoberto VelascoJulia HoeffeDiana MoldovanGraham ThompsonSuzanne SchuhJoseph J ZorcMaria KwokPrashant MahajanMichael D JohnsonRobert SapienKajal KhannaPedro RinoJavier PregoAdriana YockRicardo M FernandesIndumathy SanthanamBaljit CheemaGene OngShu-Ling ChongAndis Graudinsnull nullPublished in: Trials (2020)
The development of an international consensus on core outcomes is an important first step towards the development of consensus guidelines and standardised protocols for randomized controlled trials (RCTs) in this population. This will enable us to better interpret and compare future studies, reduce risks of study heterogeneity and outcome reporting bias, and improve the evidence base for the management of this important condition.