Clinical phenotypes and outcomes associated with SARS-CoV-2 Omicron sublineage JN.1 in critically ill COVID-19 patients: a prospective, multicenter cohort study in France, November 2022 to January 2024.

Nicolas De ProstEtienne AudureauAntoine GuillonLynda HandalaSébastien PréauAurélie GuigonFabrice UhelQuentin Le HingratFlora DelamaireClaire GrolhierFabienne TamionAlice MoisanCédric DarreauJean ThominDamien ContouAmandine HenryThomas DaixSébastien HantzClément SaccheriValérie GiordanengoTài PhamAmal ChaghouriPierre BayJean-Michel PawlotskySlim Fouratinull null

Published in: Annals of intensive care (2024)

Critically-ill patients with Omicron JN.1 infection showed a different clinical phenotype than patients infected with the earlier XBB sublineage, including more frequent obesity and less immunosuppression. Compared with XBB, JN.1 infection was not associated with higher day-28 mortality.

Keyphrases

sars cov
end stage renal disease
ejection fraction
metabolic syndrome
type diabetes
weight loss
prognostic factors
respiratory syndrome coronavirus
cardiovascular disease
cross sectional
adipose tissue
coronary artery disease
high fat diet induced
skeletal muscle
coronavirus disease