Lactate-Based Difference as a Determinant of Outcomes following Surgery for Type A Acute Aortic Dissection: A Multi-Centre Study.
Francesco NappiAlmothana AlzamilAntonio SalsanoSanjeet Singh Avtaar SinghIvancarmine GambardellaFrancesco SantiniAntonio FioreGiacomo PerocchioPierre DemondionPatrick MesnildreyThibaut SchoellNicolas BonnetPascal LeprincePublished in: Journal of clinical medicine (2023)
The arterial lactate concentration in patients referred for TAAAD is an independent factor for both operative mortality and postoperative complications. In addition to mortality, patients with an upper arterial lactate cut-off of ≥2.6 mmol/L face significant risks of VA ECMO and the need for dialysis within the first 48 h after surgery. To improve recognition and facilitate rapid transfer and surgical treatment protocol, more diligent efforts are required in the management of malperfusion in TAAAD.
Keyphrases
- aortic dissection
- end stage renal disease
- chronic kidney disease
- peritoneal dialysis
- cardiovascular events
- ejection fraction
- newly diagnosed
- minimally invasive
- randomized controlled trial
- extracorporeal membrane oxygenation
- prognostic factors
- type diabetes
- coronary artery bypass
- human health
- intensive care unit
- acute coronary syndrome
- patient reported outcomes
- quantum dots