[18F]FP-(+)-DTBZ PET study in a lactacystin-treated rat model of Parkinson disease.
Chi-Chang WengSiao-Lan HuangZi-An ChenKun-Ju LinIng-Tsung HsiaoTzu-Chen YenMei-Ping KungShiaw-Pyng WeyChing-Han HsuPublished in: Annals of nuclear medicine (2017)
In this PD model, lactacystin-induced dopaminergic terminal damage in the ipsilateral striatum could be clearly visualized through in vivo [18F]FP-(+)-DTBZ PET imaging. This may serve as a useful approach for evaluating the effectiveness of new treatments for PD.