Effect of a lifestyle intervention program with energy-restricted Mediterranean diet and exercise on the serum polyamine metabolome in individuals at high cardiovascular disease risk: a randomized clinical trial.

José C Fernández-GarcíaMaría A Martínez-SánchezMaría R Bernal-LópezAraceli Muñoz-GarachMiguel A Martínez-GonzálezMontse FitóJordi Salas-SalvadóFrancisco J TinahonesBruno Ramos-Molina

Published in: The American journal of clinical nutrition (2021)

In individuals at high CVD risk, an er-MedDiet with increased PA did not result in significant changes of serum concentrations of polyamines or related metabolites in comparison with an energy-unrestricted MedDiet and no increase in PA. This trial was registered at isrctn.com as ISRCTN89898870.

Keyphrases

cardiovascular disease
physical activity
randomized controlled trial
metabolic syndrome
clinical trial
type diabetes
ms ms
study protocol
phase iii
coronary artery disease
open label