YTHDF2 regulates MSS51 expression contributing to mitochondria dysfunction of granulosa cells in polycystic ovarian syndrome patients.

Yun-Yun JiaoNing SongXing-Yu FangXiao-Tong LuNing SunHai-Xia JinLei ChenXian-Ju HuangShuang WenZhao-Ting WuXiao-Peng WangTing-Ting ChengGui-Dong YaoWen-Yan Song

Published in: Molecular and cellular endocrinology (2024)

YTHDF2 may regulate the expression of MSS51, affecting the structure and function of mitochondria in GCs and interfering with cellular glycolysis, which may disturb the normal biological processes of GCs and follicle development in PCOS patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
poor prognosis
cell death
prognostic factors
type diabetes
adipose tissue
polycystic ovary syndrome
binding protein
signaling pathway
reactive oxygen species
long non coding rna
cell cycle arrest
patient reported
pi k akt