Comprehensive analysis of transcriptome profiles in hepatocellular carcinoma.

Yu JinWai Yeow LeeSoo Ting TohChandana TennakoonHan Chong TohPierce Kah-Hoe ChowAlexander Y-F ChungSamuel S ChongLondon L-P-J OoiWing-Kin SungCaroline G L Lee

Published in: Journal of translational medicine (2019)

Transcriptome sequencing of HCC patients reveals key cancer molecules and clinically relevant pathways deregulated/mutated in HCC patients and suggests that while HBV may integrate randomly during chronic infection, selective expression of functional chimeric transcripts likely occur during the process of tumorigenesis.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
single cell
gene expression
poor prognosis
rna seq