0.5-5% Supramolecular Salicylic Acid Hydrogel is Safe for Long-Term Topical Application and Improves the Expression of Genes Related to Skin Barrier Homeostasis in Mice Models.

Can ZhouChunting HuaQichang LiangMus'ab Al Rudaisat Siji ChenYinjing SongJiang ZhuHao Cheng

Published in: Drug design, development and therapy (2023)

Our findings demonstrated that the sustained topical administration of the 0.5-5% supramolecular SA hydrogel for up to 28 days did no harm to normal murine skin and upregulated the expression of genes related to the epidermal barrier.

Keyphrases

wound healing
poor prognosis
genome wide
drug delivery
binding protein
hyaluronic acid
metabolic syndrome
genome wide identification
gene expression
bioinformatics analysis
type diabetes
energy transfer
high fat diet induced
insulin resistance