Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection: an individual participant data meta-analysis.
Emily R SmithErin OakleyGargi Wable GrandnerKacey FergusonFouzia FarooqYalda AfsharMia AhlbergHoma AhmadziaVictor AkeloGrace AldrovandiBeth A Tippett BarrElisa BevilacquaJustin S BrandtNathalie BroutetIrene Fernández BuhigasJorge CarrilloRebecca CliftonJeanne ConryErich CosmiFatima CrispiFrancesca CrovettoCamille Delgado-LópezHema DivakarAmanda J DriscollGuillaume FavreValerie J FlahermanChristopher GaleMaria M GilSami L GottliebEduard GratacósOlivia HernandezStephanie JonesErkan KalafatSammy KhagayiMarian KnightKaren KotloffAntonio LanzoneKirsty Le DoareChristoph LeesEthan LitmanErica M LokkenValentina Laurita LongoShabir A MadhiLaura A MageeRaigam Jafet Martínez-PortillaElizabeth M McClureTori D MetzEmily S MillerDeborah MoneySakita MoungmaithongEdward MullinsJean B NachegaMarta C NunesDickens OnyangoAlice PanchaudLiona C PoonDaniel RaitenLesley ReganGordon RukundoDaljit SahotaAllie SakowiczJose Sanin-BlairJonas SöderlingOlof StephanssonMarleen TemmermanAnna ThorsonJorge E TolosaJulia TownsonMiguel Valencia-PradoSilvia VisentinPeter Von DadelszenKristina Adams WaldorfClare WhiteheadMurat YassaJim M Tielschnull nullnull nullPublished in: BMJ global health (2023)
This analysis indicates that SARS-CoV-2 infection at any time during pregnancy increases the risk of maternal death, severe maternal morbidities and neonatal morbidity, but not stillbirth or intrauterine growth restriction. As more data become available, we will update these findings per the published protocol.
Keyphrases
- birth weight
- systematic review
- pregnancy outcomes
- electronic health record
- meta analyses
- big data
- randomized controlled trial
- respiratory syndrome coronavirus
- gestational age
- early onset
- type diabetes
- weight gain
- body mass index
- adipose tissue
- skeletal muscle
- deep learning
- coronavirus disease
- artificial intelligence
- preterm birth