Clinical implications of APOBEC3A and 3B expression in patients with breast cancer.
Yong-Seok KimDer Sheng SunJung-Sook YoonYoon Ho KoHye Sung WonJeong Soo KimPublished in: PloS one (2020)
There was a difference in A3B mRNA expression levels according to breast cancer subtypes, and high levels of A3A and A3B mRNA expressions were associated with an aggressive phenotype. There was a high incidence of APOBEC3A/B deletion allele. Further studies are needed to identify the clinical significance of APOBEC in Asian patients with breast cancer.