Dysregulation of Receptor for Advanced Glycation End Products (RAGE) Expression as a Biomarker of Keratoconus.

Valentin NavelJean MalecazeCorinne BelvilleHéléna CholtusFanny HenriouxFrédéric DutheilFrançois MalecazeFrédéric ChiambarettaLoïc BlanchonVincent Sapin

Published in: Disease markers (2022)

Linked with the inflammatory process occurring in KC pathophysiology, we propose for the first time that the RAGE expression (total and truncated forms of receptor and ligands) in KC corneal tissues and tear samples provides viable biomarkers.

Keyphrases

poor prognosis
binding protein
gene expression
oxidative stress
optical coherence tomography