Loss of Chromosome 3q Is a Prognostic Marker in Fusion-Negative Rhabdomyosarcoma.
Carina A DehnerRobert C BellYang CaoKevin HeJohn S A ChrisingerAmy E ArmstrongMarielle E YoheJack F ShernAngela C HirbePublished in: JCO precision oncology (2023)
The pathogenesis of STS including FN-RMS remains poorly understood, emphasizing the need for new therapeutic advances and adequate risk stratification. Our data demonstrate that loss of chr3q is associated with poor OS in FN-RMS, supporting it as an important tool for risk stratification.