Histopathologic features predictive of metastasis and survival in 230 patients with cutaneous squamous cell carcinoma of the head and neck and non-head and neck locations: a single-center retrospective study.
M FarahD R MiltonN D GrossP NagarajanJ GuJ L CurryD IvanC A Torres-CabalaJ N MyersV G PrietoLeomar Y BallesterPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2022)
High tumour budding, LVI and ulceration are independently associated with poor outcome in cSCC and may be used to refine cSCC prognostic stratification, which is crucial to optimize clinical decision and to identify patients who are more likely to benefit from more aggressive interventions or clinical trials.