You Are What You Eat: A Review on Dietary Interventions for Treating Pediatric Nonalcoholic Fatty Liver Disease.
Piper SandelLawrence MaHelen C WangEric A PasmanPublished in: Nutrients (2023)
As the obesity pandemic worsens, cases of pediatric nonalcoholic fatty liver disease (NAFLD) and complications of this disease, such as progressive liver failure, in young adults will continue to rise. Lifestyle changes in the form of dietary modifications and exercise are currently first-line treatments. Large pediatric-specific randomized controlled trials to support specific interventions are currently lacking. A variety of dietary modifications in children with NAFLD have been suggested and studied with mixed results, including low-sugar and high-protein diets, the Mediterranean diet, and the Dietary Approach to Stop Hypertension (DASH). The roles of dietary supplements such as Vitamin E, polyunsaturated fatty acids (PUFAs), ginger, and probiotics have also been investigated. A further understanding of specific dietary interventions and supplements is needed to provide both generalizable and sustainable dietary recommendations to reverse the progression of NAFLD in the pediatric population.
Keyphrases
- young adults
- physical activity
- weight loss
- liver failure
- randomized controlled trial
- metabolic syndrome
- type diabetes
- multiple sclerosis
- blood pressure
- cardiovascular disease
- sars cov
- hepatitis b virus
- clinical trial
- body mass index
- systematic review
- risk factors
- small molecule
- skeletal muscle
- body composition
- study protocol