Bactericidal fully human single-chain fragment variable antibodies protect mice against methicillin-resistant Staphylococcus aureus bacteraemia.

Behnoush SoltanmohammadiSomayeh Piri-GavganiEilnaz BasardehMostafa GhaneiMasoumeh AziziZabihollah KhaksarZahra SharifzadehFarzad BadmastiMahdieh SoeziAbolfazl FatehParisa AzimiSeyed Davar SiadatFahimeh ShoorajSaeid BouzariMir Davood OmraniFatemeh Rahimi-Jamnani

Published in: Clinical & translational immunology (2021)

The combination therapy with anti-S. aureus scFvs and conventional antibiotics might shed light on the treatment of patients with S. aureus infections.

Keyphrases

combination therapy
methicillin resistant staphylococcus aureus
staphylococcus aureus
endothelial cells
induced pluripotent stem cells
high fat diet induced
pluripotent stem cells
adipose tissue
insulin resistance
replacement therapy