A systematic review and pooled, patient-level analysis of predictors of mortality in neuroleptic malignant syndrome.
Daniel GuinartFuminari MisawaJose M RubioJustin PereiraRenato de FilippisChiara GastaldonJohn M KaneChristoph U CorrellPublished in: Acta psychiatrica Scandinavica (2021)
Despite reliance on case reports, these findings indicate that presence of respiratory alterations, severity of hyperthermia, and older age should alert clinicians to a higher NMS mortality risk, and that antipsychotics should be stopped to reduce mortality, yet when NMS arises on LAIs, mortality is not increased vs. OAPs.