Can baseline ML Flow test results predict leprosy reactions? An investigation in a cohort of patients enrolled in the uniform multidrug therapy clinical trial for leprosy patients in Brazil.
Emerith Mayra HungriaRegiane Morillas OliveiraGerson Oliveira PennaLúcio Cartaxo AderaldoMaria Araci de Andrade PontesRossilene CruzHeitor de Sá GonçalvesMaria Lúcia Fernandes PennaLigia Regina Franco Sansigolo KerrMariane Martins de Araújo StefaniSamira Bührer-SékulaPublished in: Infectious diseases of poverty (2016)
MB and PB patients treated with R-MDT and U-MDT showed similar frequencies of RR and other clinical manifestations. Positive ML Flow tests were associated with MB leprosy and BI positivity. However, ML Flow test results at baseline showed limited sensitivity and specificity for predicting the development of leprosy reactions.