The effect of sevoflurane on retinal angiogenesis in a mouse model of oxygen-induced retinopathy.

Hee Young KimSeung-Hoon BaekSeong Wan BaikSun Sik BaeJung Min HaMinkyoung KimGyeong-Jo ByeonHye Jin KimHyun-Su RiSo Hyun Kim

Published in: Journal of anesthesia (2018)

Sevoflurane can inhibit retinal angiogenesis via suppressing VEGF expression in an OIR mice model with exposure to relative hypoxia. Nevertheless, it is still difficult to apply the results of this study immediately to humans because of the heterogeneity of responses to sevoflurane.

Keyphrases

endothelial cells
high glucose
vascular endothelial growth factor
mouse model
optical coherence tomography
diabetic retinopathy
poor prognosis
optic nerve
signaling pathway
single cell
wound healing
type diabetes
high fat diet induced
drug induced
long non coding rna
adipose tissue